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目的 观察尼莫地平联合复方丹参注射液治疗新生儿缺氧缺血性脑病 (HIE)的疗效。方法 12 8例HIE患儿随机分为复方丹参注射液组 3 2例 ,尼莫地平组 ,尼莫地平加复方丹参注射液 ,与对照组。结果 复方丹参注射液组、尼莫地平组、尼莫地平加复方丹参注射液治疗组总有效率分别为 81.3 % ( 2 6/ 3 2 )、80 .0 % ( 2 4/ 3 0 )、97.1% ( 3 4/ 3 5 ) ,对照组总有效率为 5 1.6% ( 16/ 3 1) ,P<0 .0 5。结论 尼莫地平与复方丹参注射液在治疗HIE时有协同作用 ,疗效显著 ,未见副作用发生
Objective To observe the curative effect of nimodipine combined with compound Salvia miltiorrhiza injection on neonatal hypoxic-ischemic encephalopathy (HIE). Methods A total of 12 8 HIE children were randomly divided into compound Danshen injection group (n = 32), nimodipine group (nimodipine plus compound Danshen injection), and control group. Results The total effective rate was 81.3% (26/32), 80.0% (24/30), 97.1 % (34/35). The total effective rate in the control group was 51.6% (16/3 1), P <0.05. Conclusion Nimodipine and compound Danshen injection have synergistic effect in the treatment of HIE with significant curative effect and no side effects occurred