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配制葡萄糖注射液污染铜离子的途径,主要是从原料中带入的可能性较大,其次是蒸溜水被污染,或在配制溶液过程中接触铜器而被污染,后者是较少见的。含有微量铜离子的葡萄糖溶液在 pH 值较高时,灭菌后(高温时)能显红色浑浊,放冷后红色消褪,或与强还原剂如维生素 C 配伍时,产生红色浑浊。这是由于可溶性二价铜盐溶液与碱或强还原剂作用产生氧化亚铜(红色沉淀)的原故。含有微量铜离子的注射液与氨茶碱配伍时,可变成微蓝色,这是因为氨茶碱
Preparation of glucose injection of copper ions in the way, mainly from the raw material into the possibility of a larger, followed by distilled water is polluted, or in the process of preparation of copper contact with the solution was contaminated, the latter is rare . The glucose solution containing trace amounts of copper ions shows a reddish turbidity after sterilization (at a high temperature), a reddish color after cooling, or a reddish turbidity when mixed with a strong reducing agent such as vitamin C at a high pH. This is due to the fact that soluble divalent copper salt solutions react with alkali or strong reducing agents to produce cuprous oxide (red precipitate). Injection containing a trace amount of copper ions and aminophylline compatibility, it can become slightly blue, it is because aminophylline