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目的:研究丙泊酚联合舒芬太尼或芬太尼对无痛人流患者麻醉情况及术后疼痛的影响差异。方法:选取我院自愿申请无痛人流孕妇208例,通过随机数表法分为实验组(n=104)和对照组(n=104),对照组给予丙泊酚联合芬太尼用药,实验组给予丙泊酚联合舒芬太尼用药。观察并记录患者麻醉前(T0)、麻醉后手术前(T1)、扩宫时(T2)、术后(T3)的MAP、SpO_2、RR、HR;记录患者丙泊酚用量、苏醒时间、患者醒后宫缩VAS疼痛评分;记录两组患者不良反应的发生率。结果:与T0时比较,两组在T1和T2时的MAP、SpO_2、RR、HR均有所降低,且差异有统计学意义(P<0.05),两组间比较无明显差异(p>0.05);实验组丙泊酚用量低于对照组(P<0.05);实验组的平均苏醒时间、醒后宫缩VAS疼痛评分及丙泊酚注射痛均低于对照组,差异有统计学意义(P<0.05)。实验组的恶心呕吐、呼吸抑制等不良反应发生率均较对照组有所降低,但差异无统计学意义(P>0.05)。结论:丙泊酚联合舒芬太尼较丙泊酚联合芬太尼镇痛作用更佳,术后恢复更快,值得在无痛人流手术推广使用。
Objective: To study the effects of propofol combined with sufentanil or fentanyl on the anesthesia and postoperative pain in painless abortion patients. Methods: A total of 208 pregnant women with painless application in our hospital were randomly divided into experimental group (n = 104) and control group (n = 104) by random number table. The control group was given propofol combined with fentanyl, Group was given propofol combined with sufentanil. The MAP, SpO_2, RR and HR before anesthesia (T0), before anesthesia (T1), after dilation (T2) and after operation (T3) were recorded and recorded. The patients’ Uterine contraction VAS pain score; record the incidence of adverse reactions in both groups. Results: Compared with T0, the MAP, SpO2, RR, HR of both groups decreased at T1 and T2, and the difference was statistically significant (P <0.05), there was no significant difference between the two groups (p> 0.05 ). The dosage of propofol in the experimental group was lower than that in the control group (P <0.05). The mean awakening time, uterine contraction VAS pain score and propofol injection pain in the experimental group were all lower than those in the control group P <0.05). The incidence of nausea and vomiting, respiratory depression and other adverse reactions in the experimental group were lower than those in the control group, but the difference was not statistically significant (P> 0.05). Conclusion: Compared with propofol and fentanyl, propofol combined with sufentanil has better analgesic effect and faster recovery after operation. It is worth to be used in painless abortion.