患者,男,45岁,因间断性饥饿痛伴反酸、嗳气3年加重半月于1995年8月20来我院就诊。经胃镜确诊为“十二指肠球部溃疡”,ＨＰ阴性。单纯口服奥美拉唑胶囊,20ｍｇ/ｄ,于6天后出现皮疹。首先表现为双侧上肢红色丘疹,压之褪色,继之发展至下肢及胸部,背部少见。伴皮肤瘙痒,病人未予注 Patients, male, 45 years old, due to intermittent hunger pain with acid reflux, exacerbation 3 years aggravating half month in August 1995, 20 to our hospital. The endoscopic diagnosis of “duodenal ulcer”, HP negative. Simple oral omeprazole capsules, 20mg / d, rash appeared after 6 days. First manifested as bilateral upper red pimples, pressure fade, followed by the development of the lower limbs and chest, the back of the rare. With itchy skin, the patient did not note