论文部分内容阅读
目的获取新生儿头罩给氧时供氧浓度(FsO2)、流量(Flow)与吸入氧浓度(FiO2)变化关系数据,探讨新生儿合理用氧的规律。方法用空气-氧气混合器调节FsO2和Flow,测定不同FsO2和Flow下,新生儿鼻前庭的O2浓度。结果(1)当FsO2为100%,Flow>3(L/min)时,各组头罩内新生儿鼻前庭氧浓度均>40%;Flow≥7(L/min)时,头罩内新生儿鼻前庭氧浓度在大、中头罩各组均接近60%,小头罩各组均>60%。(2)在同一型号头罩内,FsO2≥21%时,各组的头罩内新生儿的鼻前庭氧浓度差异均有统计学意义(P<0·01)。(3)在3种型号头罩内,FsO2的变化和Flow的变化均与新生儿的鼻前庭氧浓度的变化呈直线正相关关系(P均为0·000)。结论在头罩给氧下,FiO2随FsO2和Flow变化范围较大;用纯氧时,保持FiO2在安全值之下所要求的Flow较低;因此,应用空气-氧气混合器来选择合适的FsO2和Flow对于临床安全使用头罩供氧十分必要。
Objective To obtain the relationship between the concentration of oxygen (FsO2), flow and the concentration of inspired oxygen (FiO2) in the neonates during the period of oxygenation, and to explore the law of reasonable oxygen consumption in neonates. Methods FsO2 and Flow were adjusted with an air-oxygen mixer to determine the O2 concentration in the nasal vestibule under different FsO2 and Flow conditions. Results (1) When the FsO2 was 100% and Flow> 3 (L / min), the nasal vestibule oxygen concentration in each group was> 40%. When Flow≥7 (L / min) Infant nasal vestibule oxygen concentration in the large, medium hood in each group are close to 60%, small hood in each group were> 60%. (2) Within the same type of hood, the difference of nasal vestibule oxygen concentration in neonates in each group was statistically significant when FsO2≥21% (P <0.01). (3) The change of FsO2 and the change of Flow were positively correlated with the change of nasal vestibular oxygen concentration in three kinds of headgear (P = 0.000). Conclusions FiO2 varies greatly with FsO2 and Flow under hood oxygenation; with pure oxygen, lower FiO2 is required to keep FiO2 below safety; therefore, an air-oxygen mixer is used to select the appropriate FsO2 And Flow For the clinical safety of the hood oxygen is necessary.