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目的 探讨人体Al、Pb、Cr含量、三磷酸腺苷酶 (ATPase)活性与血糖之间的相关性。方法 分别检测 3 2例铝作业工人、42例Ⅱ型糖尿病患者及 3 7例健康人群的血清Al、Pb、Cr含量、红细胞膜Na+ ·K+ ATPase、Ca2 + ATPase、Mg2 + ATPase活性水平及空腹血糖 ,分析其相关性。结果 铝作业工人血Al、Pb、Cr含量及血糖水平明显高于健康对照组 ,糖尿病患者Al、Pb含量较高 ,Cr含量偏低 ,而红细胞膜Na+ ·K+ ATPase、Ca2 + ATPase、Mg2 + ATPase铝作业工人、糖尿病患者均低于健康人群。结论 铝作业工人可能因Al、Pb含量增加引起葡萄糖耐量因子 (GTF)活性降低诱发血糖升高 ,Ⅱ型糖尿病患者ATPase活性降低可能与Cr、Pb、Al含量有关
Objective To explore the correlation between Al, Pb, Cr content, ATPase activity and blood sugar in human body. Methods The levels of serum Al, Pb and Cr, the activity of Na + · K + ATPase, Ca2 + ATPase, Mg2 + ATPase in 32 cases of aluminum workers, 42 cases of type Ⅱ diabetes mellitus and 37 cases of healthy people and the levels of fasting blood glucose , Analyze its relevance. Results The contents of Al, Pb, Cr and the blood glucose in aluminum workers were significantly higher than those in healthy controls. The content of Al and Pb in diabetic patients was high and the content of Cr was low. However, the contents of Na + · K + ATPase, Ca2 + ATPase, Mg2 + ATPase Aluminum workers, diabetes were lower than healthy people. CONCLUSIONS: Al workers may reduce the activity of glucose tolerance factor (GTF) due to the increase of Al and Pb levels, and the decrease of ATPase activity may be related to the contents of Cr, Pb and Al in type II diabetic patients