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目的:观察纳洛酮对急性缺血性脑血管病昏迷患者的治疗作用。方法:57例急性缺血性脑血管病昏迷患者随机分为2组。对照组给予常规治疗,观察组在对照组治疗基础上给予纳洛酮2.0mg加入生理盐水100毫升静脉滴注,Q.8.h,疗程5天。采用G-Pcs评定疗效。结果:治疗组在治疗后4天、10天的G-Pcs平均分数均高于对照组(P<0.01或P<0.05)。结论:纳洛酮对急性缺血性脑血管病昏迷有催醒作用,且用药时间越早预后越好。
Objective: To observe the therapeutic effect of naloxone on patients with coma after acute ischemic cerebrovascular disease. Methods: 57 patients with acute ischemic cerebrovascular disease coma were randomly divided into two groups. The control group was given conventional treatment. The observation group was given naloxone 2.0mg by intravenous infusion of 100ml normal saline on the basis of the treatment of the control group, Q.8.h for 5 days. Using G-Pcs assessment of efficacy. Results: The average G-Pcs scores of the treatment group at 4 days and 10 days after treatment were higher than those in the control group (P <0.01 or P <0.05). Conclusion: Naloxone can arouse the coma of patients with acute ischemic cerebrovascular disease, and the earlier the medication is, the better the prognosis is.