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目的探讨孕晚期孕妇血脂水平与新生儿体重相关性。方法随机抽取2010年7月-2011年1月湖北省妇幼保健院孕晚期孕妇为研究对象,在研究对象知情同意后纳入本研究。根据新生儿体重分为三组不同体重组,检测孕妇血脂水平,分析孕妇血脂与新生儿体重的相关性。结果三组新生儿出生体重分别为(2 658±123)g(、3 386±203)g和(4 335±317)g,三组新生儿体重间差异有统计学意义(P<0.05)。三组新生儿孕母在TC、TG、HDL-C和LDL-C差异有统计学意义(P<0.05),而在ApoA和ApoB方面差异无统计学意义(P>0.05)。相关性分析表明,新生儿体重与孕晚期孕妇血清TC和TG正相关(P<0.05),与HDL-C和LDL-C负相关(P<0.05),与ApoA和ApoB无关(P>0.05)。结论孕妇孕晚期血脂水平可显著影响新生儿出生体重。
Objective To investigate the relationship between serum lipids and weight of newborns in the third trimester of pregnancy. Methods Pregnant women in the third trimester of pregnancy in Hubei MCH from July 2010 to January 2011 were randomly selected as research subjects and included in the study after informed consent. According to the weight of newborn, the rats were divided into three groups with different weights to detect the level of blood lipid in pregnant women and to analyze the correlation between blood lipid in pregnant women and the weight of newborns. Results The birth weights of newborns in the three groups were (2 658 ± 123) g (3 386 ± 203) g and (4 335 ± 317) g, respectively. There was significant difference in body weight between the three groups (P <0.05). There were significant differences in TC, TG, HDL-C and LDL-C between the three groups of neonates (P <0.05), but no significant difference in ApoA and ApoB (P> 0.05). Correlation analysis showed that the body weight of newborns was positively correlated with serum TC and TG (P <0.05) and negatively correlated with HDL-C and LDL-C (P <0.05), but not with ApoA and ApoB . Conclusion Pregnant women with late pregnancy serum lipid levels can significantly affect the birth weight of newborns.