先天性无虹膜(aniridia,以下简称无虹膜),是一种双侧性的、少见的全眼球疾病。除虹膜外,还累及角膜、前房角、晶体、视网膜和视神经。虹膜发育不良虽是本病最明显的临床症状,但并非影响视功能的决定因素。视力减退与黄斑中心凹未发育、视神经发育不良以及并发性白内障、青光眼和角膜混浊均有密切关系。无虹膜还可为全身性缺陷的一部分,包括智力发育迟缓,生殖器的先天异常和Wilms瘤。 Aniridia (aniridia, hereinafter referred to as no iris), is a bilateral, rare all-eye disease. In addition to the iris, but also involving the cornea, anterior chamber angle, lens, retina and optic nerve. Iris dysplasia is the most obvious clinical symptoms of the disease, but not affect the visual function of the determinants. Vision loss and macular foveal development, optic nerve dysplasia and complicated cataracts, glaucoma and corneal opacity are closely related. Non-iris can also be part of a systemic defect, including mental retardation, genital congenital abnormalities and Wilms tumor.