肿瘤干细胞与相关靶向治疗

来源 :肿瘤基础与临床 | 被引量 : 0次 | 上传用户:zcxwlh
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目前随着抗肿瘤治疗手段的改进和新药物的出现,大多数肿瘤组织或细胞能够消除,但仍有极少数细胞处于休眠状态,导致肿瘤的复发、转移。其原因可能是在肿瘤组织中存在着极少部分具有干细胞性质的细胞群体,其具有自我更新的能力和多向分化的潜能,称之为肿瘤干细胞(cancer stem cell,CSC),属单克隆起源,是形成肿瘤和肿瘤不断扩大的来源,也是肿瘤细胞对放化疗产生抵抗的原因所在。因此要从真正意义上 At present, with the improvement of anti-tumor therapy and the emergence of new drugs, most of the tumor tissues or cells can be eliminated, but a very small number of cells are still in a dormant state, resulting in tumor recurrence and metastasis. The reason may be that there are very few cell populations with stem cell properties in tumor tissue, which have the ability of self-renewal and the potential of multidirectional differentiation. They are called cancer stem cells (CSCs) , Is the source of the growing tumor and tumor, and also the reason that the tumor cells resist the radiotherapy and chemotherapy. So from the real sense
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