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目的回顾性评价肝多发海绵状血管瘤经动脉超选择性插管化疗栓塞的安全性、技术成功率及远期疗效。方法 6例肝多发海绵状血管瘤患者,采用经动脉超选择性插管并以平阳霉素碘油乳剂(PYM-Lip)实施完全性充填栓塞治疗,术后6、12、36个月行多排螺旋CT增强检查并进行相关统计学处理以评价远期疗效。结果肝多发海绵状血管瘤6例中共栓塞病灶26个,其中,成功栓塞病灶数分别为15个1例、2个4例、3个1例。26个病灶均不同程度缩小,其中,CT显示术后6、12、36个月被栓塞病灶直径缩小超过50%、直径缩小小于或等于50%、病灶消失分别为38%(10/26)、54%(14/26)、8%(2/26),62%(16/26)、23%(6/26)、15%(4/26),69%(18/26)、12%(3/26)、19%(5/26)。技术操作成功率100%,无严重并发症发生。手术前后病灶大小差异具有统计学意义(P<0.01)。结论肝多发海绵状血管瘤经动脉超选择栓塞技术操作成功率高、微创、并发症少、疗效显著。
Objective To retrospectively evaluate the safety, technical success rate and long-term efficacy of transcatheter arterial chemoembolization in the treatment of multiple cavernous hemangiomas. Methods Six patients with hepatic cavernous hemangioma were treated with transcatheter arterial superselective intubation and complete filling and embolization with PYM-Lip. After 6, 12 and 36 months Row spiral CT enhanced examination and related statistical analysis to evaluate the long-term efficacy. Results Sixteen cases of hepatic cavernous hemangioma were involved in the embolization of 26 cases. Among them, the number of successful embolization was 15 in 1 case, 2 in 4 cases and 3 in 1 case. 26 lesions were reduced to varying degrees, of which CT showed 6,12,36 months after embolization lesion diameter reduction of more than 50%, the diameter of less than or equal to 50%, the disappearance of lesions were 38% (10/26), respectively, 54% 14/26 8% 2/26 62% 16/26 23% 6/26 15% 4/26 69% 18/26 12% (3/26), 19% (5/26). Technical operation success rate of 100%, no serious complications. The size of the lesions before and after surgery was statistically significant (P <0.01). Conclusions The successful operation rate, minimally invasive and minimally invasive operation of hepatic multiple cavernous hemangiomas undergoing arterial superselective embolization is significant.