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目的:研究分析抗生素联合糖皮质激素治疗中老年慢性阻塞性肺气肿的临床效果。方法:选取我院2012年9月至2013年11月收治的140例中老年慢性阻塞性肺气肿患者,随机分为实验组和对照组,每组各70例,给予实验组抗生素联合糖皮质激素治疗,给予对照组抗生素治疗,分析两组患者的治疗效果、血气变化情况。结果:两组患者通过治疗后,实验组治疗的总有效率为92.86%,对照组治疗的总有效率为77.14%,实验组治疗的效果明显优于对照组,差异显著(P<0.05),具有统计学意义。另外,患者的临床症状、Sa O2、Pa CO2、Pa O2均有明显的改善,治疗前后差异显著(P<0.05),具有统计学意义。治疗后,实验组与对照组相比,实验组的临床症状、Pa CO2、Pa O2、Sa O2的改善效果更加明显,实验组的治疗效果明显优于对照组,差异成显著(P<0.05),具有统计学意义。结论:使用抗生素联合糖皮质激素治疗中老年慢性阻塞性肺气肿,具有较好的临床效果,有利于减轻患者的低氧症状,有效的改善患者肺功能情况,不良反应少,使用操作方法简便,具有较高的临床应用价值。
Objective: To study the clinical effect of antibiotics combined with glucocorticoid in the treatment of middle-aged and elderly patients with chronic obstructive pulmonary emphysema. Methods: A total of 140 middle-aged and elderly patients with chronic obstructive pulmonary emphysema admitted to our hospital from September 2012 to November 2013 were randomly divided into experimental group and control group, with 70 cases in each group. The patients in experimental group were given antibiotics with glucocorticoid Hormone therapy, giving the control group antibiotic treatment, analysis of the two groups of patients with treatment, blood gas changes. Results: After treatment, the total effective rate of the experimental group was 92.86%, the total effective rate of the control group was 77.14%. The effect of the experimental group was obviously better than that of the control group (P <0.05) has statistical significane. In addition, the patient’s clinical symptoms, Sa O2, Pa CO2, Pa O2 were significantly improved, before and after treatment significant difference (P <0.05), with statistical significance. Compared with the control group, the clinical symptoms, PaCO 2, PaO 2 and SaO 2 in the experimental group were significantly improved after treatment. The treatment effect in the experimental group was significantly better than that in the control group (P <0.05) ,has statistical significane. Conclusion: The combination of antibiotics and glucocorticoids in the treatment of chronic obstructive pulmonary emphysema in middle-aged and elderly patients has good clinical effect, which is beneficial to reduce hypoxia symptoms, effectively improve pulmonary function, less adverse reactions and easy to use operation method , With high clinical value.