论文部分内容阅读
目的:探讨重度子痫前期患者并发低蛋白血症与妊娠结局的相关性。方法:选择宁波市明州医院收治的重度子痫前期患者80例,依据空腹血清白蛋白结果分为非低蛋白血症组13例、轻度低蛋白血症组26例和重度低蛋白血症组41例。记录各组终止妊娠方式、终止妊娠时间、新生儿出生体重、新生儿窒息、围生儿死亡情况以及孕妇的各项并发症。结果:①随着低蛋白血症程度加重,孕妇终止妊娠时间缩短,剖宫产和治疗性引产病例及孕妇并发症发生率明显增加,自然分娩率明显下降,各组比较有统计学差异(P<0.05)。②随着低蛋白血症程度加重,新生儿出生体重下降,围生儿死亡率明显增加,三组之间比较差异均有统计学意义(P<0.01),但三组新生儿窒息发生率比较差异无统计学意义(P>0.05)。结论:重度子痫前期合并低蛋白血症,易导致孕妇及围生儿不良妊娠结局;血清白蛋白可以作为监测重度子痫前期病情严重程度的常规临床观察指标。
Objective: To investigate the correlation between hypoproteinemia and pregnancy outcome in patients with severe preeclampsia. Methods: Eighty patients with severe preeclampsia were selected from Mingzhou Hospital of Ningbo. According to the results of fasting serum albumin, 13 cases were divided into non-hypoproteinemia group, 26 cases with mild hypoproteinemia and 26 cases with severe hypoproteinemia Group of 41 cases. The method of termination of pregnancy, termination of pregnancy, birth weight, neonatal asphyxia, perinatal death and complications of pregnant women were recorded. Results: ① With the increase of hypoalbuminemia, the termination of pregnant time shortened, the incidence of cesarean section and therapeutic induction of labor and pregnant women significantly increased, the rate of natural delivery decreased significantly (P <0.05). ② With the increasing degree of hypoproteinemia, the newborn’s birth weight decreased, the perinatal mortality increased significantly, the difference between the three groups was statistically significant (P <0.01), but the incidence of neonatal asphyxia in the three groups The difference was not statistically significant (P> 0.05). Conclusion: Severe preeclampsia with hypoalbuminemia may lead to adverse pregnancy outcomes in pregnant women and perinatal children. Serum albumin may be used as a routine clinical observation indicator to monitor the severity of severe preeclampsia.