钙化防御(calciphylaxis)亦称钙性尿毒症性小动脉性病(CUA),是以系统性小动脉钙化和组织缺血坏死为特征的一种少见、致命性的血管性疾病,主要表现为皮肤溃疡、动脉血管钙化和周围组织缺血性坏死,严重者出现坏疽[1]。此病发病率低,最常见于尿毒症患者。近年来,由于对本病的认识 Calciphylaxis, also known as calcific uremic arteriole disease (CUA), is a rare, fatal vascular disease characterized by systemic arteriolar calcification and tissue ischemia and necrosis and is mainly characterized by skin ulcers , Arterial calcification and ischemic necrosis of the surrounding tissue, severe gangrene occurred [1]. The incidence of this disease is low, the most common in patients with uremia. In recent years, due to awareness of the disease