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ｈＧＨ测定对几种疾病诊断的初步探讨山西医学院第二附属医院（０３０００１）王娜，赵建瑞雁北地区药检所郭月英人生长激素（ｈＧＨ）的测定是研究生理和病理情况下垂体ｈＧＨ分泌的一项可靠方法。ｈＧＨ的分泌与调节，虽无脉冲式改变，但在下半夜至黎明时有一分泌峰。材料和方法一、应用上海生物制品研究提供的ｈＧＨ放射免疫测定药盒，用ｌｏｇ－ｌｏｇｉｔＢ／Ｂｏ计算。二、正常人８９名为本院献血员、学生及部分健康职工。年龄１５～５５岁，男７２例，女１７例。三、各类患者皆为本院内分泌门诊或住院病人。结果正常人８９例，空腹血清ｈＧＨ值为１．２４ｎｇ／ｍｌ，范围１．０１±０．２２ｎｇ／ｍｌ。成人糖尿病９例，均值为６．４８ｎｇ／ｍｌ，最高值３１．１７ｎｇ／ｍｌ。与正常人比较有显著差异。甲亢３例，均值为１．１７ｎｇ／ｍｌ，与正常人比较无差异。垂体瘤１例，均值１７６．４２ｎｇ／ｍｌ，与正常人比较有显著差异。肢端肥大症２例，均值为９５．３８ｎｇ／ｍｌ，与正常人比较有显著差异。席汉氏症３例，均值为０．３３ｎｇ／ｍｌ，与正常人比较无差异。讨论一、糖尿病患者的ｈＧＨ激素与胰高血糖素呈相对或绝对增高［１］。而ｈＧＨ被认为是引起糖尿病微血管病变的致病因素。
hGH determination of several diseases diagnosis of the first Affiliated Hospital of Shanxi Medical College (030001) Wang Na, Zhao Jianrui Yanbei drug control Guo Yueying human growth hormone (hGH) determination of physiological and pathological conditions to study the secretion of hGH pituitary A reliable method. hGH secretion and regulation, although no pulse change, but in the middle of the night until dawn when a peak secretion. Materials and methods First, the application of Shanghai biological products provide hGH radioimmunoassay kit, using log-logitB / Bo calculation. Second, the 89 normal people blood donors, students and some health workers. Aged 15 to 55 years old, 72 males and 17 females. Third, all types of patients are hospital endocrine clinic or inpatient. Results 89 cases of normal, fasting serum hGH value of 1.24ng / ml, the range of 1.01 ± 0.22ng / ml. Nine cases of adult diabetes, mean 6.48ng / ml, the highest value of 31.17ng / ml. Compared with normal people, there are significant differences. Hyperthyroidism in 3 cases, mean 1.17ng / ml, no difference compared with normal people. Pituitary tumor in 1 case, mean 176.42ng / ml, compared with normal people have significant differences. Acromegaly in 2 cases, mean 95.38ng / ml, compared with normal people were significantly different. 3 cases of Schistosoma disease, mean 0.33ng / ml, no difference compared with normal people. Discussion One, diabetic patients with hGH hormone glucagon relative or absolute increase [1]. HGH is considered to be the causative agent of diabetic microangiopathy.