目的:探讨维吾尔族和汉族妇女宫颈炎组织中TAP1、TAP2、β2-MG蛋白阳性率表达。方法:采用常规免疫组化S-P法和改良法检测65例(汉族35例,维吾尔族30例)宫颈炎组织中TAP1、TAP2、β2-MG蛋白表达。结果:TAP1、TAP2和β2-MG蛋白在改良后免疫组化S-P法中阳性率的表达为(81.54%、96.92%、95.38%),明显高于常规法(26.15%、36.92%、38.46%)(P<0.005)。结论:通过实验方法的改进,宫颈炎组织中TAP1、TAP2、β2-MG的阳性率检测明显提高,可以把它们作为宫颈炎的标记物,以提高临床上宫颈炎的检出率。 Objective: To investigate the expression of TAP1, TAP2 and β2-MG protein in cervicitis tissues of Uygur and Han women. Methods: The expressions of TAP1, TAP2 and β2-MG in 65 cases of cervicitis from 35 cases of Han and 30 cases of Uygur were detected by routine immunohistochemical S-P method and modified method. Results: The positive expression rate of TAP1, TAP2 and β2-MG protein in modified immunohistochemical SP method was (81.54%, 96.92%, 95.38%) which was significantly higher than that of routine method (26.15%, 36.92% and 38.46% (P <0.005). Conclusion: The positive rate of TAP1, TAP2 and β2-MG in cervicitis is obviously improved by the improvement of experimental methods. They can be used as markers of cervicitis to improve the detection rate of clinical cervicitis.