目的:了解我院呼吸内科住院患者抗菌药物的使用情况。方法:调查呼吸内科2003年住院病历556份,统计抗菌药的使用率、使用种类、DDDs、药敏试验、联合用药等进行分析。结果:患者抗菌药物的使用率为91％;共涉及13类64种抗菌药;DDDs排序前3位分别为:头孢曲松、罗红霉素、异烟肼;约92％的药品DUI<1,药敏试验率为33．4％;单独用药率54．7％, 联合用药率45．3％。结论:我院呼吸内科抗菌药物使用基本合理,但仍存在某些问题,应进一步提高合理用药水平。 Objective: To understand the use of antimicrobial agents in hospital respiratory medicine. Methods: Investigation of respiratory medicine in 2003, 556 inpatient medical records, statistical antibacterials utilization rate, type of use, DDDs, susceptibility testing, combination therapy analysis. Results: The usage rate of antibacterials in patients was 91%. A total of 64 antibacterials were involved in 13 categories. The top three DDDs were ceftriaxone, roxithromycin, isoniazid, and about 92% of drugs, DUI <1 , Drug sensitive test rate was 33.4%; drug alone rate of 54.7%, the combined rate of 45.3%. Conclusion: The use of antimicrobial drugs in our department is basically reasonable, but some problems still exist. We should further improve the rational use of drugs.