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目的分析东莞市2008—2010年流行性脑脊髓膜炎(流脑)的流行特征,为制定东莞市流脑防控策略提供依据。方法采用描述性流行病学分析方法对东莞市2008—2010年流脑疫情资料及健康人群带菌情况监测资料进行分析。结果 2008—2010年东莞市共发生流脑病例6例,死亡1例,年均发病率为0.027/10万;6例病例的年龄分别为:17天龄、3月龄、16岁、17岁、23岁、61岁;病例均为男性,且均为外地户籍;病例发病时间分别为1、3、4、5、8、10月。5例病例的血液或脑脊液样本培养出脑膜炎双球菌(B群2株、C群3株),1例病例的脑脊液沉渣涂片镜检发现G双球菌。2008—2010年采集不同年龄组人群咽拭子737份,分离出脑膜炎双球菌7株,其中B群6株、C群1株,人群带菌率为0.95%。结论东莞市流脑流行菌群以B群和C群为优势菌群,今后应关注菌群的变迁,继续做好流脑疫苗常规免疫接种以及流脑病原学及血清学监测工作,控制流脑发病率。
Objective To analyze the epidemiological characteristics of epidemic cerebrospinal meningitis (meningococcal meningitis) from 2008 to 2010 in Dongguan City, and provide the basis for the development of meningococcal control strategy in Dongguan City. Methods Descriptive epidemiological analysis was used to analyze the data of epidemic encephalitis in 2008 ~ 2010 in Dongguan City and the monitoring data of the carrying status of healthy people in Dongguan City. Results A total of 6 cases of epidemic encephalitis occurred in Dongguan in 2008-2010, with an average annual incidence of 0.027 / 100 000. The age of 6 cases were 17 days, 3 months, 16 years and 17 years , 23 years old, 61 years old; all cases were male, and were registered in the field; case onset time were 1, 3, 4, 5, 8, 10 months. Five cases of meningococcal meningitis (2 in group B and 3 in group C) were obtained from blood or cerebrospinal fluid samples from 5 cases. G-bacteria was found by microscopic examination of cerebrospinal fluid sediment smear in one case. From 2008 to 2010, 737 throat swabs from different age groups were collected, and 7 strains of meningococcus were isolated, of which 6 were in group B and 1 in group C, with a population carrying rate of 0.95%. Conclusion The epidemic flora of meningococcal meningitis in Dongguan City is based on B and C groups. In the future, attention should be paid to the changes of flora. Conventional immunization of meningococcal vaccine and pathogenic and serological surveillance of meningococcal meningitis should be continued. Incidence.