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一种局限于实验室使用的化学反应工艺，经过芝加哥伊利诺斯大学研究者重新修正，开发了在药物中间体方面的实际应用。该反应被称为“Swern反应”，工艺使用二甲基亚砜和草酰氯将乙醇在有机溶剂中转化成醛类和酮类。该反应经实验室化学工作者多年使用，但由于副产二甲基硫化物是
A chemical reaction process confined to laboratory use has been revised by researchers at the University of Illinois, Chicago, to develop practical applications in pharmaceutical intermediates. This reaction, known as the “Swern reaction,” involves the conversion of ethanol to aldehydes and ketones in organic solvents using dimethylsulfoxide and oxalyl chloride. The reaction was used by laboratory chemists for many years, but due to the byproduct of dimethyl sulfide