论文部分内容阅读
目的观察羟考酮缓释片与吗啡片滴定治疗中重度癌痛患者的效果。方法将2013年01月~2015年12月收治的78例伴有中重度癌症的恶性肿瘤患者随机分成两组,每组各39例,试验组采用盐酸羟考酮缓释片联合即释吗啡滴定治疗,对照组单纯采用即释吗啡滴定治疗。对比两组癌痛控制效果。结果试验组癌痛缓解率明显优于对照组(89.74%/64.10%),差异有统计学意义(P>0.05);试验组在总体生活质量、躯体功能以及情感功能方面优于对照组(P<0.05),但两组角色功能、社会以及认知功能差异无统计学意义(P>0.05)。结论羟考酮缓释片联合吗啡片滴定治疗中重度癌痛患者疗效更明确,有助于提升患者生活质量,值得借鉴和推广。
Objective To observe the effect of oxycodone sustained-release tablets and morphine tablets titration in the treatment of moderate-severe cancer patients. Methods Seventy-eight patients with malignant tumor with moderate-severe cancer who were admitted from January 2013 to December 2015 were randomly divided into two groups (n = 39 in each group). The experimental group was treated with oxycodone hydrochloride sustained-release tablets combined with immediate-release morphine titration Treatment, the control group was treated with immediate release morphine titration. Comparison of two groups of cancer pain control effect. Results The pain relief rate of the experimental group was significantly better than that of the control group (89.74% / 64.10%), the difference was statistically significant (P> 0.05). The experimental group was superior to the control group in overall quality of life, physical function and emotional function <0.05). However, there was no significant difference in the roles of function, social and cognitive function between the two groups (P> 0.05). Conclusion Oxycodone sustained-release tablets combined with morphine tablets titration for the treatment of patients with moderate-severe cancer pain more clearly, help to improve the quality of life of patients, it is worth learning and promotion.