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目的：观察循证护理对缺血性脑新生儿的临床护理效果。方法选择我院2010年1月至2015年10月收治的288例缺氧缺血性脑病新生儿，按照患儿出生先后顺序分为观察组和对照组，每组144例，两组患者儿均配合常规的治疗。在常规治疗的基础上，对照组配合常规的护理干预，观察组配合循证护理干预，观察并比较两组患儿的护理效果。结果观察组患儿的护理有效率为96.53%，对照组有效率为75.69%，P＜0.05；观察组患儿的并发症发生率更低，P＜0.05；两组患儿未出现智力异常反应，P＞0.05；观察组满意度较对照组高，P＜0.05，具有统计学意义。结论在常规治疗的基础上配合循证护理能够起到更好的效果，可以提高护理有效率，降低不良反应的发生，提高患儿家属的满意度，值得在在临床推广使用。“,”Objective To observe the evidence-based nursing of cerebral ischemic neonatal clinical care effect.Methods Select our hospital between January 2010 and October 2015 treated 288 cases of neonatal hypoxic ischemic encephalopathy (, according to child birth order divided into observation group and control group, 144 cases in each group, two groups of patients were treated with conventional.On the basis of routine therapy and control group with routine nursing intervention, the observation group with evidence-based nursing intervention, to observe and compare the effect of two groups of children with care.Results Observation group with nursing effective rate was 96.53%, effective rate was 75.69%, the control group (P < 0.05;Observation group of children with a lower incidence of complications, P 0.05;Satisfaction was high in observation group, P < 0.05, with statistical significance.Conclusion The basis of conventional treatment with evidence-based nursing can have better effect, can improve nursing efficiency, reduce the occurrence of adverse reactions, and improve the satisfaction degree of the families of children with, is worth popularizing in clinical use.