配方配料问题,是中药制剂研究中经常遇到的问题,例如某种剂型产品的配方研究,各种基质成分的配比研究等等。如何通过安排较少次数的试验,就获得精度较高且易于计算的回归方程,来描述配方组份的数量百分比与试验指标(如粘着力强度、有效期)间的关系,以利于分析最适组份配比?这涉及一类特殊的回归试验设计——混料回归设计。 The problem of formulation and ingredients is a problem often encountered in the study of traditional Chinese medicine preparations, such as the formulation of a certain dosage form product, the study of the proportion of various matrix components, and so on. How to determine the relationship between the number of formula components and the experimental indicators (such as adhesion strength and expiration date) to facilitate the analysis of the optimal group by arranging fewer trials to obtain a highly accurate and easily calculated regression equation Parts of the ratio? This involves a special type of regression test design - mixed regression design.