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目的 探讨综合干预对晚期肿瘤患者癌痛、睡眠及生命质量的影响.方法 将106例晚期肿瘤患者采用随机数字表法分为A组与B组,各53例.两组均给予常规护理干预,A组给予综合干预.于干预前后采用视觉模拟评分法、匹兹堡睡眠质量指数及生活质量量表评定患者的疼痛程度、睡眠及生命质量.结果 干预后两组视觉模拟评分法及匹兹堡睡眠质量指数评分均显著低于干预前(P＜0.01),A组较B组下降更显著(P＜0.01);两组生活质量量表评分均显著高于干预前(P＜0.01),A组较B组升高更显著(P＜0.01).结论 综合干预可以有效缓解晚期肿瘤患者的疼痛症状,显著改善其睡眠质量与生活质量.“,”Objective To investigate the effect of comprehensive intervention on cancer pain, sleep and life quality of patients with advanced cancer. Methods 106 patients with advanced cancer were randomly divided into the comprehensive intervention group (group A,n = 53) and the routine nursing group (group B,n =53) according to the random number table method. The two groups were all given routine nursing intervention, and group A was given comprehensive intervention. Before and after intervention, VAS, PSQI and SF-36 were used to evaluate the pain degree, sleep and life quality of patients. Results After intervention, VAS scores and PSQI scores of the two groups were significantly lower than those before the intervention (P＜0.01),and group A declined more significantly than group B (P＜0.01); while SF-36 scores were higher than those before the intervention (P＜0.01),and group A increased more significantly than group B (P＜0.01). Conclusion Comprehensive intervention can effectively relieve pain symptom of patients with advanced cancer, and significantly improve their sleep quality and life quality.