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目的观察脂必妥对颈动脉粥样硬化软斑块的临床疗效。方法选择北戴河疗养院2004年1月至2007年8月体检检查有颈动脉粥样硬化软斑块患者220例,随机分为两组:脂必妥组(120例)口服脂必妥3片每日2次,对照组(100例)服用辛伐他汀20 mg 每晚1次。疗程8周。比较治疗前后用彩超探测所得颈动脉软性斑块大小。结果两组治疗后斑块明显减小(P<0.01),而两组间差异无显著性意义(P>0.05)。结论脂必妥可以明显减小颈动脉粥样硬化软斑块,可作为治疗颈动脉粥样硬化的药物。
Objective To observe the clinical efficacy of Zhibituo on carotid atherosclerosis plaques. Methods 220 Beidaihe Sanatorium from January 2004 to August 2007 physical examination of carotid atherosclerosis plaques in 220 patients were randomly divided into two groups: Zhizhi appropriate group (120 cases) three oral lipid-daily 2 times, while the control group (100 cases) took simvastatin 20 mg once night. Treatment for 8 weeks. Carotid artery soft plaque size was detected by color Doppler ultrasound before and after treatment. Results The plaques in both groups were significantly decreased (P <0.01), but there was no significant difference between the two groups (P> 0.05). Conclusion Lipid can significantly reduce carotid atherosclerosis plaque, can be used as a treatment of carotid atherosclerosis drugs.