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目的评价目前高效抗逆转录病毒治疗(HAART)方案的疗效,为以后的治疗方案提供参考。方法应用国家免费提供的抗病毒治疗药品,对符合治疗条件的艾滋病病毒(HIV)感染者/艾滋病(AIDS)病例进行规范的抗病毒治疗,并检测病例的病毒载量和淋巴细胞。结果治疗1～12个月,治疗病例CD4+T淋巴细胞计数呈明显上升趋势,均值为266.2;12个月之后,CD4+T淋巴细胞计数相对稳定,均值为353.1。治疗12个月前后,其差异具有统计学意义(P<0.05)。治疗1～7个月,病例病毒载量计数呈明显下降趋势;治疗7个月之后,病例病毒载量计数相对变化较为稳定。治疗7个月前后,其差异有显著的统计学意义(P<0.01)。结论浙江省艾滋病例在接受抗病毒治疗1年后,治疗效果明显,病例状态持续稳定。
Objective To evaluate the efficacy of the current highly active antiretroviral therapy (HAART) regimen and provide a reference for future treatment regimens. Methods The antiretroviral drugs were provided free of charge in the country. The patients were treated with antiretroviral therapy according to the treatment conditions and the viral load and lymphocytes of the cases were tested. Results After treatment for 1 to 12 months, the counts of CD4 + T lymphocytes in treated patients showed a clear upward trend, with an average of 266.2. After 12 months, the CD4 + T lymphocyte count was relatively stable with a mean of 353.1. After 12 months of treatment, the difference was statistically significant (P <0.05). The treatment of 1 to 7 months, the case of viral load count showed a significant downward trend; after 7 months of treatment, the case of viral load count changes relatively stable. After treatment for 7 months, the difference was statistically significant (P <0.01). Conclusion AIDS patients in Zhejiang Province after receiving antiviral therapy for 1 year, the treatment effect is obvious, the case status remained stable.