抗胆碱能药物常常用来治疗女性尿频、尿急及急性尿失禁。α受体阻滞剂己被证明对膀胱平滑肌有调节作用,但是临床上一般不用来治疗上述病症。为此Serels S等进行了一项开放的前瞻性研究,评价这两种药物单用和联合应用治疗上述病症的临床效果。从1994年9月至1995年10月,入选34位女性患者(28～91岁,平均62岁),每天2次,每次 Anticholinergic drugs are often used to treat frequent urination, urgency, and urinary incontinence in women. Alpha blockers have been shown to modulate bladder smooth muscle but are not clinically used to treat these conditions. To this end, Serels S et al conducted an open-ended prospective study to evaluate the clinical efficacy of the two drugs alone and in combination for the treatment of the above conditions. From September 1994 to October 1995, 34 female patients (28-91 years, mean age 62) were enrolled twice daily, each time