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目的 探讨骨皮质切开术辅助正畸对骨性Ⅱ类错(牙合)畸形患者矫治时间和最终疗效的影响.方法 选择2013年12月至2016年12月于南京医科大学附属口腔医院正畸科就诊的需减数上颌第一前磨牙的骨性Ⅱ类1分类错(牙合)畸形成年患者20例,用随机数表随机分为手术组和对照组(每组10例).比较两组矫治时间的差异,并通过锥形束CT比较矫治前后软硬组织的改变.结果 手术组关闭上颌间隙时间和矫治疗程分别为(5.8±1.3)和(24.9±5.1)个月,比对照组[分别为(9.9±1.1)和(30.8±4.6)个月]均显著缩短(P＜0.01).手术组上中切牙切缘、根尖、上牙槽缘点、唇上点内收的距离及鼻唇角的增加量与对照组相比差异均有统计学意义(P＜0.05).结论 对于轻中度骨性Ⅱ类1分类错(牙合)畸形成年患者,骨皮质切开术辅助正畸不仅能缩短治疗时间,更有利于上前牙的整体内收,改善侧貌突度.“,”Objective To investigate the effect of corticotomy-facilitated orthodontics on the treatment time and final outcome in skeletal class Ⅱ division 1 patients.Methods Twenty adult skeletal class Ⅱ division 1 patients treated with two maxillary first premolar extractions were included and randomly divided into two groups (the corticotomy group and the control group).The treatment time was recorded and the changes of soft and hard tissue were compared by using three-dimensional measurement and analysis of cone-beam CT images before and after treatment.Results There was no significant difference in the alignment time between two groups,while the time of maxillary space closure and the total treatment time in corticotomy group ([5.8± 1.3] and [24.9±5.1] months,respectively) were shorter than that in the control group ([9.9 ± 1.1] and [30.8±4.6] months,respectively) and the differences were significant (P＜0.01).In the corticotomy group,the retraction amount of the upper central in cisal margin,apical tip,supradentale,labrale superius and the increase of nasolabial angle were greater than those in the control group (P＜0.05).Conclusions In patients with mild to moderate skeletal class Ⅱ division 1 malocclusion,corticotomy-facilitated orthodontics can not only shorten the treatment time,but is more conductive to the retraction of upper anterior teeth and improvement of the profile.