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目的探讨匹多莫德辅助治疗慢性支气管炎急性发作的临床疗效。方法选择我院2006年5月～2008年9月慢性支气管炎急性发作82例患者。随机分为两组,对照组给予祛痰、止咳、解痉平喘以及纠正电解质酸碱平衡紊乱,体温升高患者给予对症处理,根据病情给予吸氧和营养支持。治疗组在对照组治疗基础上给以匹多莫德口服,前2周每天口服1600mg,分2次口服,接下来2周每天口服800mg,分2次口服。观察两组患者治疗前后临床症状和体征改变情况。结果两组患者总有效率比较,差异有统计学意义(p<0.05);两组复发率比较,差异有统计学意义(p<0.05)。结论匹多莫德辅助治疗慢性支气管炎急性发作临床治疗效果显著,值得临床借鉴。
Objective To investigate the clinical efficacy of pidotimod in the treatment of acute exacerbation of chronic bronchitis. Methods 82 cases of acute exacerbation of chronic bronchitis in our hospital from May 2006 to September 2008 were selected. Randomly divided into two groups, the control group given expectorant, cough, antispasmodic and asthma and correct electrolyte acid-base balance disorders, patients with elevated body temperature given symptomatic treatment, according to the condition given oxygen and nutritional support. The treatment group was treated with pidotimod orally on the basis of the treatment of the control group. Oral administration of 1600 mg orally twice daily for the first 2 weeks followed by oral orally twice a day for 800 mg twice daily for 2 weeks. Observed two groups of patients before and after treatment of clinical symptoms and signs of change. Results The total effective rate of the two groups was statistically significant (p <0.05). There was significant difference between the two groups (p <0.05). Conclusion Pidotimod adjuvant treatment of acute exacerbation of chronic bronchitis clinical effect is significant, it is worth learning from.