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纤维支气管镜(以下简称为纤支镜)广泛地用于肺部疾病的诊断;对于肺癌的早期诊断,更是日益受到重视。但由于纤支镜取材少,组织易受挤压变形而造成误诊。我们从80年10月～85年12月收检经纤支镜取材的支气管组织共911例次(小部分病人活检1次以上),其中267例诊断为肺癌。本文就其病理类型、特征及引起误诊的原因作一分析。 材料和方法 所有病例均采用Olympus,BF—B_2或BF—B_3型纤支镜。按常规术前用药和麻醉,经鼻孔进镜。本组病例进镜取材根据临床记载仅限于段支气管开口,所以均属中央型。每例取组织2～4块,放入10％福尔马林液固定,常规脱水,石蜡包埋切片,HE染色;部分病例作爱先蓝(Alcian blue)和银纤维染色。我们复查了全部切片和临床资料,部分病例作了随访。
Fiberoptic bronchoscopy (hereinafter referred to as bronchoscopy) is widely used in the diagnosis of lung diseases; the early diagnosis of lung cancer is increasingly valued. However, due to the small number of materials taken from the bronchoscope, the tissue is susceptible to being misdiagnosed due to extrusion deformation. From October 1980 to December 2015, we collected 911 cases of bronchial tissue obtained by fiberbronchoscopy (more than one biopsy of a small number of patients), of which 267 cases were diagnosed with lung cancer. This article makes an analysis of its pathological type, characteristics and causes of misdiagnosis. Materials and Methods Olympus, BF-B_2 or BF-B_3 bronchoscopes were used in all cases. According to conventional preoperative medication and anesthesia, through the nostrils into the mirror. In this group of cases, the material taken into the lens was limited to the bronchus opening according to clinical records, so it was a central type. Two to four pieces of tissue were taken from each case, fixed in 10% formalin, dehydrated, paraffin-embedded and stained with HE. Some cases were stained with Alcian blue and silver fibers. We reviewed all the sections and clinical data, and some cases were followed up.