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近年来更多的注意力集中在用体外发射扫描对肿瘤作放射免疫学检测。对这种老的概念重新发生兴趣主要是由于减法扫描的成功。检测某些可产生各种蛋白质标记(如癌胚抗原,人的绒毛膜促性激素及甲胎蛋白)的肿瘤可得到良好结果。注意力集中在胃肠道的癌胚抗原(CEA)及乳腺癌上。曾报导检测原发及继发性肿瘤的成功率在75％以上。同位素标记的抗体可特异性地被肿瘤所摄取,其量为周围正常组织的2～5倍。此技
In recent years, more attention has been focused on radioimmunological detection of tumors using in vitro emission scans. The renewed interest in this old concept is mainly due to the success of the subtraction scan. Detection of certain tumors that produce various protein markers (such as carcinoembryonic antigen, human chorionic gonadotropin, and alpha-fetoprotein) yields good results. Attention is focused on the carcinoembryonic antigen (CEA) and breast cancer in the gastrointestinal tract. It has been reported that the success rate of detecting primary and secondary tumors is above 75%. Isotope-labeled antibodies can be specifically taken up by tumors in an amount 2 to 5 times that of surrounding normal tissue. This technique