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34只大白鼠,按每公斤体重12克飞廉的特大剂量空腹灌胃三星期后,动物生长发育情况良好,无死亡。雌、雄动物的体重皆匀速增长,增长率与对照鼠无统计学差异。肝重与体重的比例几乎相等。血象、肝功能各项指标均在正常范围内。内脏器官的大体解剖未见异常。心、肝、肺的显微结构亦未见病理变化。因而认为飞廉的毒性较小,使用较为安全。
34 rats, 12 grams per kilogram of body weight fasting gavage three weeks after fasting, animal growth and development in good condition, no death. The body weight of female and male animals kept increasing rapidly, and the growth rate had no significant difference with that of control mice. The ratio of liver weight to body weight is almost equal. Blood, liver function indicators are in the normal range. Gross anatomy of internal organs no abnormalities. Heart, liver, lung microstructure also showed no pathological changes. So that the less toxic toxicity, the use of more secure.