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目的 室内灰尘螨 (HDM)在台湾是引起变态反应最重要的室内变应原来源 ,作者准确纯化了 HDM变应原以检测大量实验对象中变应原特异的 Ig E应答 ,从而调查 HL A- 类等位基因和 Ig E对 HDM的主要变应原应答的关系 ,健全的 HL A基因定型系统为针对 HDM的变应原应答研究提供了便利
Objective Dust mites (HDMs) in Taiwan are the most important source of indoor allergens that cause allergic reactions. The author accurately purified the allergens of HDM to detect allergen-specific IgE responses in a large number of subjects to investigate HL- Class alleles and Ig E on the major allergen responses of HDM, and the robust HL A genotyping system facilitates the study of allergen response to HDM