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本文报道1991~1995年,对新疆伽师县夏普桃勒乡妇女子宫颈癌的普查结果,普查率为 76.4%,子宫颈癌初查患病率为459/10万.子宫颈癌发生与早婚、多胎产有显著相关性.应用PCR技术对普查检出的13例和该乡邻近地区同期住院的28例子宫颈浸润癌患者标本行HPV16、18型检测,阳性率分别为84.61%和82.14%,其中HPV16型占75.6%(31/41).81例子宫颈炎阳性率为 22.22%,与浸润癌检出率比较有极显著性差异(P<0.01).提示该地区子宫颈癌发生可能与HPV16、18型感染有关,特别与HPV16型感染关系更为密切.
This article reports from 1991 to 1995, the survey of cervical cancer in Shantuopeulle Township, Jiashi County, Xinjiang, the census rate was 76.4% and the prevalence rate of cervical cancer was 459 / 100000. The incidence of cervical cancer and early marriage , Multiple births were significantly correlated.Purple PCR-based detection of 13 cases and the same period in the vicinity of the township hospitalized 28 cases of cervical invasive carcinoma specimens of patients with HPV16, 18 detection, the positive rates were 84.61% and 82.14%, respectively, Among them, HPV16 type accounted for 75.6% (31/41) .The positive rate of cervicitis in 81 cases was 22.22%, which was significantly different from that of invasive carcinoma (P <0.01), suggesting that cervical cancer may be associated with HPV16 , 18 infection, especially with HPV16 infection more closely.