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目的:对腹腔镜下行卵巢囊肿剥除术患者在手术前和手术后的AMH(anti-mullerian hormone,抗苗勒氏管激素)和bFSH(basic Follicle-stimulating hormone,基础促卵泡刺激素)含量进行测定,分析其临床意义和价值。方法:将2012年1月~2014年1月期间来我院妇产科就诊的34例卵巢巧克力囊肿患者作为研究组,上述患者经相关检查均身体状况符合腹腔镜手术的要求,并选取同期36例非巧囊患者作为对照组,2组患者均实施腹腔镜下卵巢囊肿剥离术进行治疗,并分别在手术前和手术完毕时对患者的AMH和bFSH水平进行测定。结果:研究组与对照组患者在手术完毕后AMH含量[(2.02±2.11,2.77±1.62)ng/m L]同手术前[(2.88±2.30,3.08±1.81)ng/m L]对比具有明显降低,具有统计学差异,(P<0.05),研究组患者降低水平更为显著;研究组手术完毕b FSH含量(6.83±1.80)μU/m L明显高于术前(6.29±2.11)μU/m L,具有统计学差异(P<0.05),而对照组患者术后血清bFSH含量同术前比较并未明显上升,无统计学差异(P>0.05)。结论:行腹腔镜卵巢囊肿剥除术能够使患者的卵巢储备能力下降,测定AMH较b FSH能够更好的反应出卵巢手术后卵巢储备状况。
OBJECTIVE: To determine the levels of anti-mullerian hormone (AMH) and basic Follicle-stimulating hormone (bFGF) in patients undergoing laparoscopic surgery for ovarian cyst etiology before and after surgery. Determination, analysis of its clinical significance and value. Methods: From January 2012 to January 2014, 34 cases of ovarian chocolate cyst treated in obstetrics and gynecology department of our hospital were selected as the research group. All the above patients were in compliance with the requirements of laparoscopic surgery by the relevant examination, Cases of patients with non-Qiao capsule as a control group, two groups of patients underwent laparoscopic ovarian cyst dissection for treatment, and respectively at the time of surgery and surgery at the time of AMH and bFSH levels were measured. Results: Compared with those before operation (2.88 ± 2.30, 3.08 ± 1.81) ng / m L], AMH levels in study group and control group after operation were significantly higher than those before operation [(2.02 ± 2.11,2.77 ± 1.62) ng / m L] (6.83 ± 1.80) μU / m L in the study group was significantly higher than that of the preoperative (6.29 ± 2.11) μU / m 2, which was statistically significant (P <0.05) (P <0.05). However, the serum bFGF level of patients in the control group did not increase significantly compared with that before operation (P> 0.05). Conclusions: Laparoscopic ovarian cyst extirpation can reduce the ovarian reserve capacity of patients, and AMH can better reflect ovarian reserve after ovarian surgery than b FSH.