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近年来，一些资料表明阿斯匹林对结直肠癌有预防作用犤１～３犦。研究发现规律服用阿斯匹林１年以上者罹患结肠癌的机率可降低５０％～６０％。阿斯匹林等非甾体类抗炎药物预防肿瘤的作用机制可能是由于花生四烯酸代谢过程中的限速酶COX－２（cyclooxy－genase－２）受到抑制。
In recent years, some data show that aspirin has a preventive effect on colorectal cancer 犤 1 ~ 3 犦. The study found that regularly taking aspirin more than 1 year risk of colon cancer can be reduced by 50% to 60%. The mechanism by which aspirin and other non-steroidal anti-inflammatory drugs prevent tumors may be due to the inhibition of cyclooxygenase-2 (COX-2), a rate-limiting enzyme in the metabolism of arachidonic acid.