一百多年前,2型糖尿病还被视作是一种少见的疾病,但近年来,其发病呈爆发式增长。大约1,600万美国人患有2型糖尿病,并且至少有相同数量的人糖耐量受损。中国是糖尿病大国,估计现有糖尿病患者4,000万,90％以上为2型糖尿病。80％的糖尿病患者因冠心病而死亡。胰岛素抵抗和高胰岛素血症不仅是2型糖尿病,也是糖耐量受损人群的特点。这些代谢紊乱,与高血压和血脂异常一起常常出现在2型糖尿病和糖耐量受损的人群中,明显增加了心血管病、周围血管病和脑血管病的发病风险。 One hundred years ago, type 2 diabetes was also seen as a rare disease, but its incidence has exploded in recent years. Approximately 16 million Americans have type 2 diabetes and have at least the same number of impaired glucose tolerance. China is a major diabetic country with an estimated 40 million existing diabetics and more than 90% with type 2 diabetes. 80% of diabetic patients die of coronary heart disease. Insulin resistance and hyperinsulinemia are not only type 2 diabetes but also a hallmark of people with impaired glucose tolerance. These metabolic disorders, often associated with hypertension and dyslipidemia, occur in people with type 2 diabetes and impaired glucose tolerance and significantly increase the risk of cardiovascular disease, peripheral vascular disease and cerebrovascular disease.