由于生理解剖特点形成屏障,抗菌药不容易在人体某些部位达到有效浓度。在治疗颅内、骨髓、前列腺、胰腺等部位感染时,需要选择在特殊部位浓度较高的药物。根据抗菌药物的药动学特点及抗菌谱合理选择抗菌药,在临床中医务人员应引起高度重视。 Due to the physiological anatomical features of the formation of barriers, antimicrobial agents are not easily reached in some parts of the body to an effective concentration. In the treatment of intracranial, bone marrow, prostate, pancreas and other parts of the infection, the need to choose a higher concentration of drugs in special parts. According to the pharmacokinetic characteristics of antimicrobial drugs and antimicrobial spectrum reasonable choice of antimicrobial agents, medical personnel in the clinic should be highly valued.