论文部分内容阅读
本文对40例肝炎后肝硬变、13例正常人的脑脊液中16种氨基酸水平进行了检测,并同时检测了血清中氨基酸水平.结果表明:肝炎后肝硬变患者血浆氨基酸谱与脑脊液氨基酸谱完全不同.作者对肝炎后肝硬变患者脑脊液中氨基酸代谢的特点和失衡机理进行了探讨,并探讨了测定脑脊液中氨基酸水平的临床意义:①鉴别肝性昏迷和非肝性昏迷.②对于判定肝组织损伤程度,判定肝性脑病发生率和判定肝硬变预后较血清氨基酸敏感.③指导临床应用支链氨基酸的用时、用法和用量.
In the present study, 16 amino acids in cerebrospinal fluid (CSF) of 40 cirrhotic posthepatitic cirrhosis patients and 13 normal controls were detected, and serum amino acid levels were also measured.The results showed that plasma amino acid profile and cerebrospinal fluid amino acid profile Completely different.According to the characteristics and imbalance mechanism of amino acid metabolism in cerebrospinal fluid of patients with posthepatitic cirrhosis, the author discussed the clinical significance of measuring amino acid in cerebrospinal fluid: (1) identification of hepatic coma and non-hepatic coma Liver tissue damage, determine the incidence of hepatic encephalopathy and determine the prognosis of cirrhosis than serum amino acid sensitivity. ③ guide the clinical use of branched-chain amino acids, usage and dosage.