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目的观察利福平联合阿奇霉素治疗小儿难治性支原体肺炎疗效。方法将66例患儿随机分为对照组32例、观察组34例,观察症状、体征及胸部X线、住院时间。结果观察组加用利福平后临床症状、体征减轻和消失的时间明显短于对照组,平均住院日也明显缩短,二组比较差异有统计学意义(P<0.05)。结论联合应用利福平治疗肺炎支原体肺炎,对于缩短发热时间,减轻咳嗽,促进啰音消失,降低平均住院天数均有较好的疗效,且用药安全,不良反应小,值得推广应用。
Objective To observe the effect of rifampin combined with azithromycin in the treatment of refractory mycoplasma pneumonia in children. Methods Sixty-six children were randomly divided into control group (n = 32) and observation group (n = 34). Symptoms and signs, chest X-ray and hospital stay were observed. Results Compared with the control group, the clinical symptoms, signs and symptoms disappeared in the observation group were significantly shorter than those in the control group, and the average length of stay was also significantly shortened. The difference between the two groups was statistically significant (P <0.05). Conclusions The combined application of rifampicin in the treatment of Mycoplasma pneumoniae pneumonia has a good curative effect in shortening the fever time, relieving the cough, promoting the disappearance of rales and reducing the average length of stay, and is safe to treat and has a small adverse reaction. It is worth popularizing and applying.