近年来 ,高血压与肾脏损害的关系 ,日益受到基础研究与临床实践的关注。业已证明 ,因为降压治疗心脑血管病发生率有较大幅度下降 ,而高血压是加重肾功能恶化的重要危险因素之一 ,2 5 %终未期肾脏病变 (ESRD)与高血压病有关。肾脏既是血压调节的重要器官 ,又是高血压累及的重要 In recent years, the relationship between hypertension and renal damage has been increasingly concerned by basic research and clinical practice. It has been shown that the incidence of cardiovascular and cerebrovascular diseases is greatly reduced due to antihypertensive treatment, and hypertension is one of the important risk factors that aggravate the worsening of renal function. Twenty-five percent of the patients with end-stage renal disease (ESRD) are associated with hypertension . Kidney is not only an important organ of blood pressure regulation, but also an important factor involved in hypertension