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本文采用钙调素（CaM）免疫组化定位技术，经DAB显色观察问情期兔、假孕兔、假孕后经雌、孕激素或来非司酮处理兔卵巢和子宫中CaM的分布。结果显示：不同生殖激素状态下兔卵巢（基质和黄体）、子宫（内膜及肌层）组织均可见CaM免疫反应阳性产物（显色剂DAB的棕色颗粒）存在，但其数量随激素状态而变化。卵巢中，间情期最低，假孕兔及假孕后雌、孕激素处理兔次之，假孕后米非司酮处理兔最高。子宫中，间情期最低，假孕兔次之，假孕后雌、孕激素或米非司酮处理克最高。提示CaM可能参与哺乳动物卵巢激素分泌功能的调节，并与卵巢激素对子宫生长、内膜发育等调控作用密切相关。
In this paper, calmodulin (CaM) immunohistochemical localization technique was used to observe the distribution of CaM in the ovary and uterus of female rabbits, pseudo-pregnant rabbits, pregnant women after estrogen, progesterone or nifepristone by DAB colorimetry . The results showed that CaM immunoreactive positive products (brown particles of DAB) were observed in the tissues of ovary (matrix and corpus luteum), uterus (intima and myometrium) in different reproductive hormones, Variety. Ovary, the lowest between the period of love, fake pregnant women and pregnant women after pregnancy, progesterone treatment of rabbits, mifepristone after pregnancy the highest rabbit. Uterus, the lowest between empathy, fake pregnancy, followed by pregnancy, females, progesterone or mifepristone treatment g highest. These results suggest that CaM may be involved in the regulation of ovarian hormone secretion in mammals and is closely related to the regulation of ovarian hormones on uterine growth and intima development.