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为了探讨高分级肿瘤对手术治疗结肠癌结果的确切影响,研究者纳入了2004~2011年其所在中心接受手术治疗的散发性结肠癌患者,就其远处和淋巴结扩散率,复发多变量警戒率(mH R)以及总体及疾病致死率进行了分析。结果发现,在922例有明确肿瘤分级患者中,175例(19.0%)患者为高分级肿瘤,这些患者有更高的淋巴结转移风险(63.8%比39.6%,P<0.001)和
In order to investigate the exact impact of high-grade tumors on the surgical treatment of colon cancer, the investigators enrolled patients with sporadic colon cancer who underwent surgery at their center from 2004 to 2011. In terms of their distant and lymph node spreads, relapse multivariable alertness rates (mH R) and overall and mortality rates were analyzed. RESULTS: Among 922 patients with definite tumor grade, 175 (19.0%) had high-grade tumors with a higher risk of lymph node metastasis (63.8% vs. 39.6%, P <0.001) and