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目的:研究分析脓毒症应用不同剂量血必净的急诊治疗效果。方法:选取2012年9月—2015年7月就诊的90例脓毒症患者,征得患者及其家属同意后,以随机的方式将90例患者分为三组,即A组、B组和C组,每组30例,三组患者均给予常规治疗,在此基础上,A组加用小剂量血必净,B组加用中剂量血必净,C组加用大剂量血必净,比较分析三组患者治疗效果。结果:和A组、B组相比,C组患者体温(T)、心率(HR)、C-反应蛋白水平(CRP)、呼吸频率(RR)、降钙素原(PCT)、白细胞计数(WBC)以及白细胞介素-18(IL-18)治疗后改善情况更优,组间数据比较差异有统计学意义(P<0.05)。结论:在脓毒症常规治疗的基础上,大剂量使用血必净,可有效改善患者炎症反应和预后。
Objective: To study and analyze the emergency treatment effect of sepsis with different doses of Xuebijing. METHODS: Ninety sepsis patients were selected from September 2012 to July 2015. After consenting patients and their families, 90 patients were randomly divided into three groups: group A, group B and group B Group C, 30 cases in each group, the three groups were given routine treatment, on this basis, A group with a small dose of Xuebijing, B group with a medium dose Xuebijing, C group with a large dose of Xuebijing , Comparative analysis of three groups of patients with treatment. Results: Compared with group A and group B, the changes of body temperature, heart rate, CRP, RR, PCT, WBC) and interleukin-18 (IL-18), the difference between the two groups was statistically significant (P <0.05). Conclusion: Based on the routine treatment of sepsis, high dose of Xuebijing can effectively improve the inflammatory response and prognosis of patients.