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目的探讨泛昔洛韦治疗复发性生殖器疱疹(GH)的临床疗效。方法选取大同市第三人民医院2014年10月—2015年10月收治的复发性GH患者102例,随机分为观察组与对照组,各51例。观察组患者给予泛昔洛韦治疗,对照组患者给予阿昔洛韦治疗,7 d为1个疗程,连续服用12个疗程,比较两组患者治疗效果、复发率及不良反应发生率、症状改善时间。结果观察组患者临床疗效优于对照组,复发率、不良反应发生率低于对照组,止疱时间、疼痛减轻时间、结痂时间短于对照组(P<0.05)。结论泛昔洛韦治疗复发性GH的临床疗效确切,可有效改善患者临床症状,且复发率、不良反应发生率低。
Objective To investigate the clinical efficacy of famciclovir in the treatment of recurrent genital herpes (GH). Methods 102 cases of recurrent GH patients admitted to the Third People’s Hospital of Datong from October 2014 to October 2015 were randomly divided into observation group and control group, with 51 cases in each group. The patients in observation group were treated with famciclovir. The patients in control group were treated with acyclovir. After 7 days, they took one course of treatment and took 12 courses continuously. The treatment effect, recurrence rate and incidence of adverse reactions were compared between the two groups. Results The clinical efficacy of the observation group was better than that of the control group. The recurrence rate and the incidence of adverse reactions were lower in the observation group than in the control group. The blister time, pain relief time and scab time were shorter than those in the control group (P <0.05). Conclusion Famciclovir treatment of recurrent GH clinical curative effect is exact, can effectively improve the clinical symptoms, and the recurrence rate, the incidence of adverse reactions low.