由于非洲抗氯喹恶性疟的扩散以及现有抗疟药的费用较大和其潜在毒性,奎宁又成为一种重要的抗疟药。有关非洲儿童最近使用奎宁的资料较少,作者等在扎伊尔金沙萨某医院对重症恶性疟儿童进行了奎宁静脉给药的临床和疗效观察。选择原虫血症密度≥5%、有严重精神神经症状需静脉给药的 Quinine has also become an important antimalarial drug because of the spread of the anti-chloroquine-resistant Plasmodium falciparum in Africa and the cost and potential toxicity of existing antimalarials. There is relatively little information on the recent use of quinine in African children, and the authors observed the clinical and curative effects of quinine intravenously on children with severe malaria in a hospital in Kinshasa, Zaire. Protozoospermia density selection of ≥ 5%, severe neurological symptoms need intravenous administration