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目的分析和探讨不同方案治疗青春期多囊卵巢综合征患者的临床效果。方法 93例确诊为青春期多囊卵巢综合征患者,随机分成对照组(46例)与研究组(47例),对照组单纯给予炔雌醇环丙孕酮进行治疗,研究组在对照组治疗的基础上联合使用补肾活血中药进行治疗,比较两组患者治疗前后的体质量指数、血睾酮、空腹胰岛素、空腹血糖改善以及停药后疾病复发率等情况。结果经过3个疗程的治疗,研究组患者体质量指数、血睾酮、空腹胰岛素、空腹血糖改善显著优于对照组(P<0.05);研究组患者停药后其临床复发率低于对照组(P<0.05);停药6个月后两组的各指标比较差异具有统计学意义(P<0.05)。结论临床上采用炔雌醇环丙孕酮联合补肾活血中药治疗青春期多囊卵巢综合征能取得更好的疗效,其显著降低了患者停药后的疾病复发情况,值得临床借鉴。
Objective To analyze and discuss the clinical effects of different regimens in the treatment of adolescent polycystic ovary syndrome patients. Methods Ninety-three patients with polycystic ovary syndrome diagnosed as adolescent were randomly divided into control group (n = 46) and study group (n = 47). The control group was treated with ethinylestradiol and cyproterone alone. The treatment group Based on the combination of Chinese medicine for the treatment of kidney and blood circulation, body mass index before and after treatment in both groups were compared, blood testosterone, fasting insulin, fasting blood glucose and improve the disease recurrence rate after stopping. Results After 3 courses of treatment, the body mass index, serum testosterone, fasting insulin and fasting blood glucose in study group were significantly better than those in control group (P <0.05). The clinical relapse rate in study group was lower than that in control group P <0.05). There was significant difference between the two groups after six months’ withdrawal (P <0.05). Conclusion Clinically, ethinyl estradiol, cyproterone combined with tonifying kidney and activating blood circulation medicine can achieve better curative effect in adolescent polycystic ovary syndrome, which significantly reduces the relapse of the disease after the drug is discontinued, which deserves clinical reference.