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目的:观察中西医结合治疗慢加急(亚急性)肝衰竭(ACLF)的临床疗效,探究治疗安全性。方法:选取60例ACLF患者作为研究对象,随机分为联合组和西药组各30例。西药组常规给予西医基础治疗+支持治疗+抗病毒治疗等,联合组在西药组治疗的基础上给予中医辨证施治,比较两组患者的治疗效果。结果:经治疗后,两组患者总效率及ALT、ALB、AST、PTA、TBIL等指标比较差异均有统计学意义(P<0.05)。结论:中西医结合治疗ACLF疗效优于西医治疗,安全性好,值得临床推广应用。
Objective: To observe the clinical curative effect of combining traditional Chinese and western medicine in the treatment of slow plus urgency (subacute) hepatic failure (ACLF) and explore the therapeutic safety. Methods: Sixty patients with ACLF were selected as study subjects and randomly divided into 30 cases in combination group and western medicine group. The western medicine group routinely gave western medicine basic therapy + supportive therapy + antiviral therapy and so on. On the basis of the western medicine group, the combined group gave TCM syndrome differentiation and treatment, and compared the curative effect of the two groups. Results: After treatment, the total efficiency and ALT, ALB, AST, PTA, TBIL and other indicators were significantly different (P <0.05). Conclusion: The combination of traditional Chinese and western medicine is superior to western medicine in the treatment of ACLF, which is safe and worthy of clinical application.