肛管及直肠发生恶性黑色素瘤属少见病例,而发生有黑色素和无黑色素之恶性黑色素瘤并存者更不易见到。我科四十年来仅见此1例,现报道如下。患者男,60岁,农民,脓血便二个月余,大便次数10～20次/日,一直为脓血便伴肛周疼痛,入院查体:患者恶病质。心、肝、肺、脾无异常。肛门处有一脱出物,约枣大小,暗紫色,易出血。肛诊:胸膝位2～7点肛内6cm处有一个高低不平、质地硬之肿物。 Malignant melanoma in the anal canal and rectum is a rare case, and coexisting malignant melanomas with melanin and melanin are less likely to be seen. For the past 40 years, our department has only seen one case. The report is as follows. Male patient, 60 years old, farmer, pus and blood will be more than two months, stool frequency 10 to 20 times / day, has been accompanied by perianal pain pus and blood, admission examination: patient cachexia. There are no abnormalities in heart, liver, lungs and spleen. There is a prolapse in the anus, about jujube size, dark purple, easy bleeding. Anal diagnosis: There is a bumpy and hard mass in the anus of 6 to 7 points in the chest and knee position.