巨细胞瘤好发于四肢管状骨,特别是膝关节上下端之长骨;发生于头颈部者较少。著者根据文献综述指出:头颈部巨细胞瘤多发生于下颌骨,其次为上颌骨、筛骨、额骨、蝶骨、颧骨,颞骨较少,喉部者更为罕见。患者年龄多在20—40岁,占总数75％左右。女性较男性略多。X线摄片检查肿瘤在长骨中呈“肥皂泡状”为其特点;而颞骨鳞部、乳突及颧骨之巨细胞瘤则呈骨质破坏或骨质缺损。 Giant cell tumors occur in the extremities of tubular bones, especially the long bones of the upper and lower ends of the knee; fewer occur in the head and neck. According to the literature review, the authors pointed out that head and neck giant cell tumors usually occur in the mandible, followed by the maxilla, ethmoid bone, frontal bone, sphenoid bone, and sacrum. The sacrum is rare, and the larynx is more rare. Patients are mostly between 20 and 40 years old, accounting for about 75% of the total. Women are slightly more than men. X-ray examination of the tumor in the long bone was “soap bubble-like” for its characteristics; while the tibial scaly, mastoid and sacrum giant cell tumor showed bone destruction or bone defect.