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目的:观察脑血管疾病血清白蛋白(A),球蛋白(G),白蛋白与球蛋白比率(A/G)的变化特点及临床意义。方法:回顾性分析135例脑血管病患者血清A、G、A/G变化,其中脑血栓形成77例,脑出血48例,短暂性脑缺血发作(TIA)10例,并与47例年龄、性别相匹配的健康人A、G、A/G进行对比。结果:脑血管病与健康对照组比较,A降低,脑血栓有显著性差异(P<0.005),脑出血与TIA无显著性差异(P>0.05)。G升高、A/G下降,均有显著性差异。脑血管病中,不同性别间、高血压与正常血压组间、老年与非老年组间比较,A、G、A/G均无显著差异(P>0.05)。结论:低A、高G、低A/G可能是脑血管病的危险因素之一。
Objective: To observe the changes and clinical significance of serum albumin (A), globulin (G), albumin and globulin ratio (A / G) in patients with cerebrovascular diseases. Methods: A retrospective analysis of 135 cases of cerebrovascular disease serum A, G, A / G changes, including cerebral thrombosis in 77 cases, 48 cases of cerebral hemorrhage, transient ischemic attack (TIA) in 10 cases, and 47 cases of age , Sex matched healthy people A, G, A / G for comparison. Results: Compared with healthy control group, cerebrovascular disease had a lower A, a significant difference in cerebral thrombosis (P <0.005), and no significant difference between cerebral hemorrhage and TIA (P> 0.05). G increased, A / G decreased, there was a significant difference. There were no significant differences in A, G and A / G between the two groups (P> 0.05), between different genders, between hypertension and normal blood pressure group, and between the elderly and the non-elderly group. Conclusion: Low A, high G, low A / G may be one of the risk factors of cerebrovascular disease.